Sant’Anastasia al Palatino Church Rome

The Sant’Anastasia al Palatino Church is one of the oldest churches in Rome and the first one that was built within the original city center. It is also the only church in Rome that stays open 24 hours a day.

Sant’Anastasia al Palatino Church Rome

Address, opening hours and admission

Sant'Anastasia al Palatino Church Rome
Sant’Anastasia al Palatino Church

Address: Piazza di Sant’Anastasia – Rome (tel. +39 06 6782980). Opening hours: All day, 24/7. Closed: Never. Admission: Free. The archeological remains below the church cannot be visited at the moment (January 2018).

History and description

Saint Anastasia was crucified and died a martyr in Dalmatia in the year 304 (on December 25). According to one legend the church is built on top of the ruins of her husband Publio‘s (who had left her a widow at a relatively young age) house.

The church was originally constructed towards the end of the 4th century, enlarged (by order of Pope Leo III) in the year 700 and reconstructed under Sixtus IV (1478).

Underneath the lower part of the Santa Anastasia Church the ruins of an insula, dating back to he times of the Roman Empire, can be found. An insula can be compared to a modern condominium.

The church has two bell towers. Its facade was designed by Luigi Amigucci and stems from the middle of the 17th century.

The interior is divided into three naves.

What to see

The statue below the altar is of Saint Anastasia herself, while the painting above it is by Domenichino and depicts Saint Jerome.


Tomb of Angelo Mai (Sant'Anastasia al Palatino Rome)
Tomb of Angelo Mai and Madonna statue.

Cardinal Angelo Mai (1782-1854) is one of the people buried inside the church. He is famous for rescuing famous texts from oblivion by deciphering their palimpsests (manuscript documents from which the text has been removed in order to be able to reuse them). His tomb was made by the neoclassical sculptor Giovanni Maria Benzoni.


Ceiling fresco by Michele Cerruti (Sant'Anastasio al Palatino Rome)
“Martyrdom of St. Anastasia”

The ceiling fresco depicts the Martyrdom of Saint Anastasia and was painted by Michelangelo Cerruti. Cerruti (1663-1748) was probably born in Rome and studied under the master of perspective, Andrea Pozzo. His work can be admired in several famous churches, including San Pietro in Montorio, Sant’Antonio dei Portoghesi and Santa Maria Sopra Minerva.

Piazza di Sant’Anastasia – Rome

1 thought on “Sant’Anastasia al Palatino Church Rome

  1. Rebecca says:

    Basilica of St Anastasia

    In the 14th century, a lead box was discovered in the church containing the “Veil of Our Lady” woven in thread of different colours, and the “Mantle of St Joseph”. These relics are thought to have been brought from the Holy Land by St Jerome. At the beginning of the 5th century.

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